71481 AIDS Working for a World free of I n 2012, the global AIDS response is at a critical juncture. There is much to celebrate: According to UNAIDS, the global rate of new HIV infections declined 23% in the past decade. AIDS treatment costs have dropped 100-fold since 2000 from more than $10,000 to under $100 per person annually, and more than 8 million people in develop- ing countries are receiving lifesaving treatment. Antiretroviral drugs have allowed people with access to these drugs to live long, productive lives and for mothers living with HIV to have healthy, HIV-free babies. The vast global resources mobilized for AIDS have not only directly helped HIV and AIDS patients and their families in developing countries, but also have helped expand access to primary health care, rebuild health facili- ties, train health workers, and strengthen laboratories, procurement and supply chains, and health information systems. Yet despite these remarkable successes, AIDS remains a critical In 2012, despite remarkable development challenge, particularly in Africa. successes, AIDS remains a Since 1981, more than 65 critical development challenge, million people have been infected and 30 million particularly in Africa. have died of AIDS-related causes. 2.7 million people were newly infected in 2010, including 390,000 children. Every minute, a young woman is infected with HIV. At least 7 million people living with HIV in developing countries are not receiving life- saving medicines. In Swaziland, half of pregnant women are HIV-positive. Zambia loses half of the teachers it trains annually to AIDS. Pressures on donor aid budgets due to the global economic downturn — and a growing sense of complacency due to the recent progress in confronting the epidemic — now threaten to reverse these gains. In many countries, the health sector is too weak or fragmented to deliver an effective and sustainable response to AIDS. If these trends continue, the world will not reach Millennium Development Goal (MDG) 6 to halt and reverse the spread of HIV and AIDS by 2015 — and this will also have a negative impact on reaching all of the other MDGs. WorkING for A WorlD frEE of AIDS 1 But there is hope. Today, global understanding of the diverse drivers of the epidemic is greater than ever before, with scientific progress helping governments better target populations most at-risk and the behaviors most likely to spread HIV. There is a firmer grasp of the ways the epidemic is evolving in different parts of the world, and better policies in place to mitigate the social and economic devastation caused by AIDS. Advocacy for HIV and AIDS has spurred a massive global health movement, spawning numerous research initiatives, new funding mechanisms, and civil society networks, which in turn have expanded support, heightened awareness, and reduced stigma. International donors have provided tens of billions for prevention, treatment, and care for HIV and AIDS in low- and middle-income countries, including more than $4.6 billion committed by the World Bank since 1989. a game changer The Bank’s global AIDS response was very limited until 2000, when the Bank declared AIDS one of its seven corporate priorities and subsequent- ly launched the first-ever $1 billion AIDS prevention and mitigation effort, known as the Multi-country AIDS Program (MAP). The Bank’s strong advocacy helped catalyze and transform the global AIDS response from a multi-million to a multi-billion dollar effort. Nearly 40 percent of the Bank’s AIDS funds went to community organizations for grassroots actions to reduce stigma, change behaviors and social norms to prevent infection, and care for people and orphans affected by HIV. overall, the Bank has provided support to 50,000 community-based organizations in more than 50 countries to tackle HIV and AIDS. The Bank’s strategy crossed borders and sectors to bring comprehensive actions to the rural villagers, truck drivers, sex workers, and others most at-risk of infection. And the Bank’s actions helped trigger an unprecedented wave of global donor support, with the subsequent creation of the United States President’s Emergency Plan for AIDS relief (PEPfAr) and the Global fund for AIDS, Tuberculosis, and Malaria (GfATM). The Bank’s AIDS response through the MAP was a breakthrough in several critical ways. The Bank broke global and national silence on the 2 THE WorlD BANk The World Bank helped catalyze and transform the global AIDS response from a multi-million to a multi-billion dollar effort. epidemic, and sparked broad and high-level political will to act. The Bank found creative ways to get support quickly to those most in need, and instituted a flexible approach to financing that could span countries and sectors, and be adapted in response to changing environments and new information. Bank-supported projects under the MAP were able to move from conception to execution faster than a typical development project. To qualify, countries had to demonstrate that they had a solid strategic national plan, a high-level government commitment to act fast, and willingness to channel money to civil society groups and community organizations. Countries that previously were unwilling to admit they had an AIDS epidemic soon began lining up for funding. The result was a major scaling-up of AIDS-related services that saved countless lives in Africa, as well as a quantum increase in the actions of African countries to confront HIV, which was emulated in other regions of the world and replicated years later to respond to the global outbreak of avian flu. By 2009, the Bank’s Fund for the Poorest, the International Development Association (IDA), had supported AIDS projects in 67 countries. results included: ■ 1.5 million women provided with drugs to prevent mother-to-child HIV transmission ■ 1,500 new voluntary counseling and testing sites established, enabling nearly 7 million people to be tested for HIV ■ More than 173 million people benefited from HIV prevention services ■ More than 1 billion condoms distributed The Bank continues to provide support to some of the populations most impacted by HIV. for example in Swaziland, which has the highest HIV WorkING for A WorlD frEE of AIDS 3 prevalence in the world at 26% among the sexually active population (15-49 years), HIV-related illnesses have become the major cause of morbidity and mortality among children under age five. Approximately a third of Swazi children are orphans and vulnerable children (oVC), and this number is expected to grow. Bank support is helping establish a conditional cash transfer (CCT) system to support households caring for oVC; the stipends are provided if caregivers can verify that the children are going to school and receiving proper nutrition and health care, including immunizations. Power of prevention The extraordinarily high social and economic costs of the current HIV and AIDS crisis points to the need for more effective prevention approaches. Bank support for HIV and AIDS prevention efforts have included innovative strategies that aim to change cultural norms by tackling taboos about sex, gender power relations, and stigmas associ- ated with particular at-risk groups. Some methods have proven highly successful: for example, Bank work with partners to promote male circumcision in eastern and southern Africa is helping to curb the spread of HIV. Bank support for a regional project in West Africa’s main transport corridor helped reduce sexually transmitted infections, including HIV, by more than 20 percent in 4 years. Campaigns to delay the age of sexual initiation have also succeeded in some countries. The Bank has provided Supporting evidence-based national responses. In Brazil, with early support support to 50,000 from the Bank, the government took ag- community-based gressive measures to fight the disease, targeting at-risk groups, raising public AIDS organizations awareness of the importance of using condoms, and setting up voluntary testing in more than 50 centers for sex workers. Brazil has also countries. realized a rapid expansion of primary 4 THE WorlD BANk health care through its family Health Strategy, with a focus on the poorest parts of the country, which led to a doubling in coverage between 2001 and 2011, reducing infant mortality. The Bank is sup- porting the establishment and evaluation of 15 regional health net- works designed to improve the efficiency and quality of health care. Bank support has also played a pivotal role in turning the tide on HIV and AIDS in India. An independent impact evaluation of the India AIDS program concluded that it will have prevented 60 percent of the expected number of HIV infections between 1995 and 2015, primarily through targeted behavioral interventions for sex workers and their clients. In 2012, the Bank continues to provide critical financing for India’s national AIDS program. Targeting girls and young women. Empowering school-age girls and their families can have substantial effects on their sexual and reproduc- tive health, helping them access education, delay marriage, increase self-esteem, practice safe sex, and find good jobs. Recent Bank studies tested the use of CCTs in Tanzania and Malawi as a tool to reduce the risk of HIV or other sexually transmitted infections. Both studies suggest that financial incentives could be a powerful prevention tool for HIV/STI infection among young people. In Tanzania, participants showed a 27% reduction in the incidence of STIs after one year; in Malawi, adolescent girls showed a two-thirds reduction in the risk of HIV infection. The Bank is further testing this idea in a high HIV-prevalence setting in lesotho; further evidence is needed before concluding that this can be an efficient, scalable, and sustainable HIV prevention strategy. Promoting healthy development Today, we know that AIDS is not one epidemic, but many. The HIV virus mutates at a faster rate than any other known virus, creating multiple strains that travel and propagate through multiple complex social networks. The epidemic permeates societies, crosses borders, and spreads at different rates and in different at-risk groups. There is no easy, one-size-fits-all solution. Age, gender, education, poverty, and employment WorkING for A WorlD frEE of AIDS 5 all factor into the probability of contracting the disease, requiring countries to develop strong surveillance and epidemic intelligence to determine the drivers of their epidemics and to create unique and adaptable responses for treatment and prevention. Advances in medicine have also changed the context for AIDS response at global and country levels. Drugs for HIV-positive pregnant women have dramatically reduced the number of infants born with HIV. Antiret- roviral drugs have transformed a diagnosis of HIV from a death sentence into a manageable disease for those with access to treatment. In response to this changing environment, today the Bank’s approach to confronting the HIV and AIDS pandemic has also evolved. The focus of the Bank’s 2007 strategy for health, nutrition, and population, Healthy De- velopment, is helping low- and middle-income countries strengthen their health systems to save lives and ensure healthy futures for their people. With strong health systems, countries can capitalize on the gains of disease-specific programs and ensure they are sustainable in the future. rwanda is an example of a country where the government recognized early on the interface between strengthening the wider health sector and scaling up the response to HIV and AIDS. Bank funds were used to scale up AIDS treatment and to strengthen the health system through performance-based financing (PBF) for HIV/AIDS services and annual grants to health facilities. Bank support for integrated, incentivized AIDS-related services contributed to a 76% increase in utilization of health services, and the provinces served by the Bank’s project experienced higher rates of HIV testing than others. In addition, Bank-led pooled AIDS drug procurement initiatives were subse- quently adopted by the wider rwandan health sector. A Bank-supported project in West Africa’s main transport corridor helped reduce sexually transmitted infections, including HIV, by more than 20 percent over 4 years. 6 THE WorlD BANk Bank HIV investments have also strength- ened health delivery models by promot- With Bank support, ing innovation and generating evidence of what works. A positive impact evaluation India’s national of the PBf program for HIV services in AIDS program will rwanda has contributed to wider and successful adaptation of this approach have prevented in health. An independent Indian govern- ment review of CSo funding concluded 60 percent of the that CSo performance management was expected number stronger in AIDS than other sectors and recommended that lessons be applied to of HIV infections other fields of health delivery. In Brazil, the between 1995 Bank is supporting an effort to pioneer performance-based financing of AIDS and 2015. CSo activities, with important implica- tions for wider health delivery. A key challenge and opportunity for countries is to optimize the use of disease-specific investments also to enhance wider health service delivery and improve broader health outcomes, with the goal of reaching all of the MDGs. The fiscal challenge of aidS The Bank remains committed to financing innovative and effective ap- proaches to AIDS prevention and to undertaking extensive analytical work to deepen understanding of the epidemic and how it spreads, its development impacts, and the most fiscally sustainable responses to HIV and AIDS. The Bank also will continue to provide technical assis- tance to countries to strengthen their national AIDS strategies and plans. But providing treatment for everyone who needs it remains a fiscal chal- lenge for many developing countries. In 2011, 8 million people who were living with HIV and AIDS in low- and middle-income countries were receiving lifesaving antiretroviral WorkING for A WorlD frEE of AIDS 7 medications — an extraordinary achievement. But the sobering reality is that at least 7 million adults living with HIV who need treatment still lack access to lifesaving drugs, and each year 2-3 million people become newly infected with HIV. Although treatment costs per person have plummeted, as countries scale up their efforts to treat more people — a lifetime commitment — the financial burden on governments continues to grow. The results of a 2012 World Bank analysis of the fiscal impact of AIDS in selected African countries are sobering: ■ Botswana: About one-quarter of the sexually active population is living with HIV. The fiscal costs of HIV will peak at 3.5% of GDP around 2016, slowly falling to 3.3% of GDP by 2030 if new infec- tions decline. With mining revenues slowing down relative to GDP, the fiscal costs of HIV/AIDS could rise to over 12% of government revenues by 2021, presenting an extraordinary fiscal challenge. ■ South Africa: Almost one in five of all HIV infections globally are in South Africa. The fiscal impact of HIV in that country includes both health and social welfare costs, especially grants for orphans. HIV costs in South Africa may peak at about 1% of GDP between 2012 and 2016, declining thereafter if current prevention efforts are successful. ■ Swaziland: With the highest HIV prevalence globally, and declining economic and revenue projections, Swaziland presents a particularly urgent challenge. The costs of HIV may reach 7.3 percent of GDP by 2020, requiring a scale up in HIV financing will need to increase substantially. ■ Uganda: Costs are estimated to rise to over 3 percent of GDP from 2012-2016. External funds account for about 85 percent of all HIV financing. The cost of a single HIV infection is 12 times GDP per capita ($5,900 per new infection as of 2010). These findings demonstrate the major fiscal challenges facing some highly impacted countries. Middle-income, fast-growing, and resource-rich countries may be able to finance an increasing share of their AIDS treat- ment costs if they are able to prioritize human development investments. The challenge will be most acute in slow-growing and low-income econo- mies. Assisting countries to project, plan for, and diversify their financing is an increasingly important part of the Bank’s work on HIV and AIDS. 8 THE WorlD BANk Promoting efficiency and effectiveness Increasingly, the Bank is helping countries improve the efficiency, effectiveness, and sustainability of their national AIDS responses. The Bank has assisted over 120 countries to better understand their epidem- ics and develop better prioritized, strategic plans, and is working with high-incidence countries to determine the optimal mix of interventions to avert as many new infections as possible. The Bank supports countries to strengthen implementation procedures, demonstration and training sites, management and monitoring systems, and incentives to improve delivery in high-burden countries with the goal of increasing implementation ef- ficiency without reducing the quality of health care services. The Bank is also developing multi-method approaches for large-scale, population- level evaluations of complex AIDS interventions. And the Bank is helping countries project the fiscal dimensions of AIDS so they can transition from an emergency response effort to sustainable, nationally owned and inte- grated plans. The Bank works in partnership with the United States and United kingdom governments and UNAIDS in these efforts. In Nigeria, for example, the Bank is partnering with the US and Nigerian governments to improve the efficiency and effectiveness of HIV preven- tion programs with focus on the most at-risk populations that are the main drivers of the country’s epidemic. The Bank is also supporting the government to better plan, target and coordinate the national HIV and AIDS response, determine the most efficient The Bank is helping service delivery models, and convert these into national policy, with the aim of averting countries improve most of the estimated 300,000 new HIV infections each year. the efficiency, effectiveness, and HIV prevention remains critical but chal- lenging. In countries where HIV spreads sustainability of through the general population, the best their national AIDS prevention requires changes in behavior that are often hard to bring about, while responses. proven methods to halt an epidemic WorkING for A WorlD frEE of AIDS 9 concentrated in one at-risk group may be politically difficult to employ. one method stands out: Male circumcision has proven to curb the spread of HIV and has been highly successfully employed. The Bank is working with the US government to quantify the savings over a 15 to 20 year period that governments in East and Southern Africa will incur if they invest early on in male circumcision programs for HIV preven- tion, specifically in the 14 countries with both high HIV prevalence and few circumcised males that are the focus of a multi-partner global male circumcision scale-up strategy. This analysis helps governments both reduce the rate of new infection and reduce costs by investing in proven prevention technologies. Another example of how the Bank is helping generate knowledge of what works is a UK-financed, Bank-executed evaluation of community responses to HIV in 8 countries. The evaluation provides strong evidence that specific community interventions can have a positive effect on the course of the epidemic by increasing HIV knowledge, reducing stigma, and increasing condom use, HIV testing uptake, treatment adherence, and use of health services. A key contribution of the Bank to the global AIDS response is helping countries understand their epidemics, and the importance of targeting the most at-risk populations. In 2011, the Bank developed a ground- breaking HIV report that has led to program shifts in the Middle East and A key challenge and opportunity for countries is to optimize the use of disease-specific investments to enhance wider health service delivery and improve broader health outcomes, with the goal of reaching all of the MDGs. 10 THE WorlD BANk North Africa (MENA) region. Characterizing the HIV/AIDS Epidemic in MENA shows how focusing investments on prevention efforts for priority populations at increased risk of HIV infection can yield long-term health and social benefits. As a result, the governments of Egypt, Morocco, Jordan, Sudan, and Syria have increased their resource allocation to most at-risk populations. Also in 2011, a study by the Bank, UNDP, and WHo entitled The Global HIV Epidemics Among Men Who Have Sex with Men (MSM): Epidemiology, Prevention, Access to Care, and Human Rights evaluates the global costs of inaction in addressing HIV within this at-risk population, reviews epidemiological evidence of HIV transmission and evidence of efficacy and intervention costs, and models the costs and impact of addressing the needs of this population. looking ahead to 2015 and beyond Credible projections suggest that about 60 percent of new HIV infec- tions in the next decade could be averted if three global goals are met: ■ 15 million people receive antiretroviral treatment by 2015 ■ 20 million men are circumcised in 13 countries in Eastern and Southern Africa with high rates of HIV and low rates of male circumcision ■ 80% of at-risk populations in the 30 countries with 80% of all new infections receive key interventions, including pregnant women, sex workers, men who have sex with men, and intravenous drug users As the world looks toward 2015 and beyond, the Bank stands ready to build on the results that have been achieved in the global fight against HIV and AIDS and intensify its efforts to help countries reach all of the MDGs — mindful of the challenges that the global HIV and AIDS epidemic continues to pose to human development. The Bank is committed to doing its part to help developing countries realize the dream of a world free of AIDS and poverty, and healthier, brighter futures for all of their citizens. WorkING for A WorlD frEE of AIDS 11 For more information please visit: www.worldbank.org/aids www.worldbank.org/health Follow us on Twitter at @worldbankhealth